During a televised interview on WBZ-TV with host Jon Keller, Murray, who served under five governors over 22 years, noted that both Romney, a Republican, and Patrick, a Democrat, had experience in business before being elected.
"I think that they didn't quite have the understanding of how the process works within the building itself, but within government," she said.
Murray, who is launching her own business development company, added, "Government does not move very quickly which is why I'm excited about going to the private sector where you can actually move things."
First woman President of the Massachusetts State Senate
The first woman elected president of the Senate, Murray said the political culture in Massachusetts is only "a little" more welcoming to women now than when she was first elected to the Senate.
She said that when women run for higher office, the media describes their hair and clothing instead of focusing on their ideas. "They are held to a different standard," she said.
Asked if that had hurt Martha Coakley as she was edged in November by Governor-elect Charlie Baker, Murray noted Coakley had been outspent and said, "Part of that is always there, always there for women candidates."